Metastatic lung cancer in pregnancy - a diagnostic and management challenge: A case report

Authors

  • Dr. Mwangi C.M Department of Obstetrics and Gynecology, University of Nairobi, Nairobi, Kenya.
  • Dr. Omwodo K.A Department of Reproductive Health, Moi University, Eldoret, Kenya.
  • Dr. Osoti A.O Senior Lecturer, Consultant Obstetrician-Gynecologist, Clinical Epidemiologist, University of Nairobi, Nairobi, Kenya, Associate Professor of Global Health – Public Health, University of Washington, Washington, United States.

DOI:

https://doi.org/10.59692/jogeca.v33i2.440

Keywords:

Lung cancer, Small cell carcinoma, pulmonary tuberculosis

Abstract

Background: Lung cancer during pregnancy remains an uncommon occurrence. As of 2016, there were less than 70 histologically confirmed lung cancer in pregnancy cases reported in the literature. 

Case presentation: A 29-year-old woman presented with a chronic cough in the second trimester of pregnancy at the Kenyatta National Hospital (KNH) as a referral. Treatment for Pulmonary Tuberculosis (PTB) was initiated in a peripheral facility based on suggestive signs on the chest radiograph. Symptoms persisted while on anti-TB medication. On further evaluation, she was diagnosed with advanced squamous cell lung cancer. The patient went into spontaneous labor and vaginally delivered a fresh stillbirth. She received palliative care, and succumbed from disease progression.  

Conclusion: Lung cancer during pregnancy exhibits similar clinical presentation to prevalent conditions, especially in low-resource and TB prevalent settings, and pose challenges in early diagnosis, and consequently, poor outcome. Chronic cough should raise suspicion for malignancy and prompt investigation. 

Author Biographies

  • Dr. Mwangi C.M, Department of Obstetrics and Gynecology, University of Nairobi, Nairobi, Kenya.

      Department of Obstetrics and Gynecology, University of Nairobi, Nairobi, Kenya.

  • Dr. Omwodo K.A, Department of Reproductive Health, Moi University, Eldoret, Kenya.

     Department of Reproductive Health, Moi University, Eldoret, Kenya.

  • Dr. Osoti A.O, Senior Lecturer, Consultant Obstetrician-Gynecologist, Clinical Epidemiologist, University of Nairobi, Nairobi, Kenya, Associate Professor of Global Health – Public Health, University of Washington, Washington, United States.

    Senior Lecturer, Consultant Obstetrician-Gynecologist, Clinical Epidemiologist, University of Nairobi,  Nairobi, Kenya.

    Associate Professor of  Global Health – Public Health, University of Washington, Washington, United States.

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Published

2021-03-31

How to Cite

Metastatic lung cancer in pregnancy - a diagnostic and management challenge: A case report. (2021). Journal of Obstetrics and Gynaecology of Eastern and Central Africa, 33(2), 51-54. https://doi.org/10.59692/jogeca.v33i2.440

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